My research focuses on the combustion characteristics of fossil fuels and alternative fuels at engine operating conditions, which is related to various environmental and energy issues. Specifically, I conducted numerical simulations of flame initiation and propagation processes to understand the complicated chemistry-transport coupling in flame dynamics and further quantify the global combustion properties such as flame burning velocities and minimum ignition energies (MIEs). On a fundamental level, these global properties are critical targets for oxidation mechanism development and validation of both traditional fuels and alternative fuels. On a practical level, they affect the fuel burning rate and stability of Internal Combustion (IC) engines and hence determine the engine’s performance as well as pollutant emissions. Moreover, in spark-ignition engines, minimum ignition energy is a key parameter in the engine modeling and is essential for the design of high-efficiency and low-emission engines.